Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | SPR | P35270 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734541 | 1.00 | TACR1 (0.58) | TACR1NPSR1BLMALDH1A1MAPT | |
| SCHEMBL30359421 | 0.91 | TACR1 (0.60) | TACR1NPSR1BLMALDH1A1MAPT | |
| SCHEMBL16626133 | 0.89 | IL1RN (0.56) | TACR1NPSR1BLMALDH1A1MAPT | |
| SCHEMBL23501915 | 0.88 | KMT2A (0.62) | NPSR1BLMALDH1A1MAPTCYP1A2 | |
| SCHEMBL23501914 | 0.88 | KMT2A (0.62) | NPSR1BLMALDH1A1MAPTCYP1A2 | |
| SCHEMBL19252917 | 0.88 | NPSR1 (0.63) | NPSR1BLMALDH1A1MAPTCYP1A2 | |
| SCHEMBL3043368 | 0.88 | NPSR1 (0.63) | NPSR1BLMALDH1A1MAPTCYP1A2 | |
| SCHEMBL5115709 | 0.88 | HTR2C (0.56) | NPSR1BLMALDH1A1MAPTCYP1A2 | |
| SCHEMBL2857033 | 0.87 | MTNR1A (0.61) | TACR1BLMALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2857036 | 0.87 | MTNR1A (0.61) | TACR1BLMALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |