Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 5/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | TACR1 | P25103 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625066 | 0.92 | IL1RN (0.55) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL16618099 | 0.91 | TACR1 (0.59) | IL1RNERAP2ERAP1TACR1CTSL | |
| SCHEMBL29138492 | 0.89 | TACR1 (0.63) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL6362124 | 0.89 | TACR1 (0.63) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL16626132 | 0.89 | TACR1 (0.63) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL6355051 | 0.89 | TACR1 (0.63) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL11734541 | 0.89 | TACR1 (0.58) | TACR1MEN1KMT2APOLBKDM4E | |
| SCHEMBL6984435 | 0.89 | TACR1 (0.58) | TACR1MEN1KMT2APOLBKDM4E | |
| SCHEMBL31070801 | 0.89 | IL1RN (0.67) | IL1RNERAP2ERAP1TACR1MEN1 | |
| SCHEMBL3046095 | 0.86 | GAA (0.54) | IL1RNERAP2ERAP1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307548-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | CHANG GUNG UNIVERSITY (TW) | 2015-10-29 | — | — | US | disclosed |
| US-20150099691-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | CHANG GUNG UNIVERSITY (TW) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307548-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | FPR1, FPR3, FPR2 | IL1RN 221/4885ERAP2 2239/4885ERAP1 960/4885 |
| US-20150099691-A1 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF | FPR1, FPR3, FPR2 | IL1RN 221/4885ERAP2 2239/4885ERAP1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.