SCHEMBL6984812

SCHEMBL6984812

O=C1Oc2cc(O)ccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.57
TYR P14679 4/20 0.57
MAOB P27338 4/20 0.57
CISD1 Q9NZ45 2/20 0.55
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
RECQL P46063 2/20 0.51
POLB P06746 1/20 0.51
RAB9A P51151 1/20 0.51
KDM4E B2RXH2 1/20 0.51
PSMD14 O00487 1/20 0.51
AURKA O14965 1/20 0.51
NPC1 O15118 1/20 0.51
DAPK3 O43293 1/20 0.51
JAK2 O60674 1/20 0.51
STK17B O94768 1/20 0.51
ALPL P05186 1/20 0.51
ALPI P09923 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11219422 0.83 TYR (0.54) MAOATYRMAOBCISD1MEN1
SCHEMBL7549906 0.81 TYR (0.51) MAOATYRMAOBCISD1MEN1
SCHEMBL23728337 0.80 MAOA (0.54) MAOATYRMAOBCISD1MEN1
SCHEMBL2114477 0.80 MAOA (0.49) MAOATYRMAOBCISD1MEN1
SCHEMBL14259795 0.80 MAOA (0.49) MAOATYRMAOBCISD1MEN1
SCHEMBL28936587 0.78 TYR (0.53) MAOATYRMAOBCISD1MEN1
SCHEMBL29391946 0.78 TYR (0.53) MAOATYRMAOBCISD1MEN1
SCHEMBL11069101 0.77 MAOA (0.51) MAOATYRMAOBCISD1MEN1
SCHEMBL3513089 0.76 MAOA (0.41) MAOATYRMAOBCISD1MEN1
SCHEMBL5707772 0.75 MAOB (0.83) MAOATYRMAOBCISD1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1330645-C Benzofuran-2-ones as colorants for organic materials CIBA SC HOLDING AG (CH) 2007-08-08 CN disclosed
EP-1159276-B1 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS CIBA SC HOLDING AG (CH) 2003-10-22 EP disclosed
CN-1343207-A Benzofuran-2-ones as colorants for organic materials CIBA SC HOLDING AG (CH) 2002-04-03 CN disclosed
EP-1159276-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS Ciba SC Holding AG (CH) 2001-12-05 EP disclosed
WO-2000053597-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-14 WO disclosed