Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | TYR | P14679 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798008 | 0.76 | MIF (0.47) | MAOATYRMAOBCISD1RAB9A | |
| SCHEMBL6984812 | 0.76 | MAOA (0.57) | MAOATYRMAOBCISD1MEN1 | |
| SCHEMBL3848115 | 0.69 | STK17B (0.38) | MAOATYRMAOBMEN1KMT2A | |
| SCHEMBL705239 | 0.66 | ACHE (0.39) | MAOBMEN1KMT2APOLBRAB9A | |
| SCHEMBL7549906 | 0.64 | TYR (0.51) | MAOATYRMAOBCISD1MEN1 | |
| SCHEMBL3513421 | 0.64 | TYR (0.40) | MAOATYRMAOBRECQLCDK5 | |
| SCHEMBL23728337 | 0.64 | MAOA (0.54) | MAOATYRMAOBCISD1MEN1 | |
| SCHEMBL14259795 | 0.64 | MAOA (0.49) | MAOATYRMAOBCISD1MEN1 | |
| SCHEMBL2114477 | 0.64 | MAOA (0.49) | MAOATYRMAOBCISD1MEN1 | |
| SCHEMBL11219422 | 0.63 | TYR (0.54) | MAOATYRMAOBCISD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100285502-A1 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. | 2010-11-11 | — | — | US | disclosed |
| US-7544498-B2 | Aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2009-06-09 | — | — | US | disclosed |
| US-20080274478-A1 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TOL, LTD. | 2008-11-06 | — | — | US | disclosed |
| US-7361483-B2 | Aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-04-22 | — | — | US | disclosed |
| US-20060183211-A1 | Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. | 2006-08-17 | — | — | US | disclosed |
| WO-2006081537-A2 | NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2006-08-03 | — | — | WO | disclosed |