Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15606823 | 0.86 | LMNA (0.49) | LMNAHSD17B10HPGDRECQLNPC1 | |
| SCHEMBL13073767 | 0.85 | LMNA (0.47) | LMNAHSD17B10HPGDRECQLNPC1 | |
| SCHEMBL20040048 | 0.83 | LMNA (0.50) | LMNAHSD17B10HPGDRECQLNPC1 | |
| SCHEMBL23430551 | 0.82 | LMNA (0.51) | LMNAHSD17B10HPGDRECQLNPC1 | |
| SCHEMBL43357 | 0.82 | HPGD (0.66) | LMNAHSD17B10HPGDRECQLSMN1; SMN2 | |
| SCHEMBL4718747 | 0.80 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4637521 | 0.80 | HPGD (0.42) | HPGDRECQLNPC1RAB9ASMN1; SMN2 | |
| Methylene Chloride SCHEMBL27882742 | 0.79 | HPGD (0.59) | LMNAHSD17B10HPGDRECQLSMN1; SMN2 | |
| Acetic Acid SCHEMBL7381337 | 0.79 | HPGD (0.62) | LMNAHSD17B10HPGDRECQLSMN1; SMN2 | |
| SCHEMBL3415092 | 0.78 | HPGD (0.49) | HPGDNPC1RAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320529-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-25 | — | — | EP | disclosed |
| EP-1305308-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| EP-1214314-A2 | AMINOPIPERIDINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2002024684-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002008224-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001007432-A2 | AMINOPIPERIDINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-02-01 | — | — | WO | disclosed |