Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718747 | 0.96 | HPGD (0.46) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL3415092 | 0.94 | HPGD (0.49) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL22169189 | 0.85 | CA2 (0.40) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL22169212 | 0.84 | USP2 (0.39) | HPGDSMN1; SMN2USP2NAMPTNR1H2 | |
| SCHEMBL4716609 | 0.81 | HPGD (0.44) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL4714585 | 0.80 | HPGD (0.46) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL6984870 | 0.80 | LMNA (0.47) | HPGDSMN1; SMN2EPHX1NPC1RAB9A | |
| SCHEMBL1848025 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL861278 | 0.77 | USP2 (0.64) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL5199652 | 0.77 | HPGD (0.50) | HPGDSMN1; SMN2USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951678-A1 | PYRAZOLE COMPOUNDS HAVING CANNABINOID RECEPTOR (CB1) ANTAGONIZING ACTIVITY | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007046550-A1 | PYRAZOLE COMPOUNDS HAVING CANNABINOID RECEPTOR (CB1) ANTAGONIZING ACTIVITY | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-04-26 | — | — | WO | disclosed |