Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951664 | 0.68 | HTR2A (0.32) | — | |
| SCHEMBL1577842 | 0.67 | HTR2A (0.41) | — | |
| SCHEMBL6709305 | 0.67 | EDNRA (0.34) | RIPK1 | |
| SCHEMBL4600218 | 0.67 | — | — | |
| SCHEMBL6984486 | 0.65 | KMT2A (0.34) | — | |
| SCHEMBL3539241 | 0.65 | APEX1 (0.37) | — | |
| SCHEMBL7425481 | 0.64 | HTR2A (0.32) | — | |
| SCHEMBL15653605 | 0.64 | HTR2A (0.32) | — | |
| SCHEMBL2508140 | 0.64 | HTR2A (0.35) | — | |
| SCHEMBL6601729 | 0.64 | HTR2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244446-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1244446-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001039773-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |