Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639115 | 0.68 | HTR2C (0.36) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL2165693 | 0.68 | KMT2A (0.36) | KMT2ALMNAMAPTMEN1HTR2C | |
| Methane SCHEMBL6545484 | 0.67 | KMT2A (0.36) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL6151708 | 0.66 | ACHE (0.52) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL5175848 | 0.65 | TDP1 (0.33) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL6984973 | 0.65 | RIPK1 (0.32) | — | |
| SCHEMBL9458426 | 0.64 | OPRK1 (0.43) | KMT2AMAPTMEN1TDP1L3MBTL1 | |
| SCHEMBL9288607 | 0.64 | LMNA (0.41) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL9802086 | 0.63 | KMT2A (0.41) | KMT2ALMNAMAPTMEN1HTR2C | |
| SCHEMBL9378737 | 0.63 | KMT2A (0.41) | KMT2ALMNAMAPTMEN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244446-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1244446-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001039773-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |