Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | ACACA | Q13085 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 3/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986945 | 0.88 | F10 (0.53) | F10KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6985167 | 0.88 | F10 (0.53) | F10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6986369 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTSTAT3L3MBTL3 | |
| SCHEMBL6986950 | 0.83 | F10 (0.53) | F10KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6986450 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTSTAT3L3MBTL3 | |
| Hydrochloric Acid SCHEMBL6987729 | 0.81 | F10 (0.49) | F10KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6600677 | 0.74 | F10 (0.53) | F10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4832287 | 0.73 | SCD (0.50) | KDM4EALDH1A1STAT3L3MBTL3L3MBTL1 | |
| SCHEMBL6986879 | 0.72 | KMT2A (0.42) | F10KDM4EALDH1A1MAPTL3MBTL3 | |
| Hydrochloric Acid SCHEMBL6494015 | 0.72 | KMT2A (0.41) | F10KDM4EALDH1A1MAPTL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |