Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL4888055 | 0.87 | TTR (0.38) | TTR | |
| SCHEMBL27808905 | 0.87 | — | — | |
| Tetrahydrofuran SCHEMBL3866495 | 0.87 | ALDH1A1 (0.50) | — | |
| Dioxane SCHEMBL8962544 | 0.76 | — | — | |
| Dioxane SCHEMBL4481844 | 0.76 | TTR (0.40) | TTR | |
| SCHEMBL4442942 | 0.76 | — | — | |
| SCHEMBL6919 | 0.76 | — | — | |
| SCHEMBL4888046 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL29071846 | 0.71 | — | — | |
| Oxirane SCHEMBL45627 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | claimed |
| US-6495576-B2 | N-(1-((3,4-DIOXO-2-(3-PYRIDINYLAMINO)-1-CYCLOBUTEN-1-YL)AMINO) -2,2-DIMETHYLPROPYL)-4-METHYLBENZAMIDE FOR EXAMPLE; TREATING BLADDER OVERACTIVITY, BENIGN PROSTATIC HYPERPLASIA, PREMATURE LABOR, AND SEXUAL DISORDERS | ABBOTT LABORATORIES | 2002-12-17 | — | — | US | claimed |
| US-20020165264-A1 | Aminal diones as potassium channel openers | ABBOTT LABORATORIES | 2002-11-07 | — | — | US | claimed |
| US-20020147230-A1 | Aminal Diones as potassium channel openers | ABBOTT LABORATORIES | 2002-10-10 | — | — | US | claimed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |
| CN-101998932-B | Novel precursor for preparing lithium composite transition metal oxide | LG CHEMICAL LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-102983320-A | Lithium secondary battery | LG CHEMICAL LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-101765934-B | Positive electrode active material for lithium secondary battery, method for producing same, and lithium secondary battery | NIPPON CHEMICAL IND | 2013-03-06 | — | — | CN | disclosed |
| CN-102484250-A | Positive Electrode Active Material, Method For Producing Same, And Nonaqueous Electrolyte Secondary Battery Using Same | SUMITOMO METAL MINING CO JP | 2012-05-30 | — | — | CN | disclosed |
| CN-101601163-B | Lithium secondary battery with improved high-temperature cycle life characteristics | LG CHEMICAL LTD | 2011-11-16 | — | — | CN | disclosed |
| CN-101998932-A | Novel precursor for preparing lithium composite transition metal oxide | LG CHEMICAL LTD | 2011-03-30 | — | — | CN | disclosed |
| CN-101765934-A | Positive electrode active material for lithium secondary battery, method for producing same, and lithium secondary battery | NIPPON CHEMICAL IND | 2010-06-30 | — | — | CN | disclosed |
| CN-101601163-A | Lithium secondary battery with improved high-temperature cycle life characteristics | LG CHEMICAL LTD (KR) | 2009-12-09 | — | — | CN | disclosed |
| CN-100499213-C | Non-aqueous electrolyte secondary battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1897332-A | Non-aqueous electrolyte secondary battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2007-01-17 | — | — | CN | disclosed |
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| US-6495576-B2 | N-(1-((3,4-DIOXO-2-(3-PYRIDINYLAMINO)-1-CYCLOBUTEN-1-YL)AMINO) -2,2-DIMETHYLPROPYL)-4-METHYLBENZAMIDE FOR EXAMPLE; TREATING BLADDER OVERACTIVITY, BENIGN PROSTATIC HYPERPLASIA, PREMATURE LABOR, AND SEXUAL DISORDERS | ABBOTT LABORATORIES | 2002-12-17 | — | — | US | disclosed |
| US-20020165264-A1 | Aminal diones as potassium channel openers | ABBOTT LABORATORIES | 2002-11-07 | — | — | US | disclosed |
| US-20020147230-A1 | Aminal Diones as potassium channel openers | ABBOTT LABORATORIES | 2002-10-10 | — | — | US | disclosed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147230-A1 | Aminal Diones as potassium channel openers | KCNJ2, KCNJ11, KCNH1 | TTR 2975/4885MEN1 773/4885KMT2A 1875/4885 |
| US-20020165264-A1 | Aminal diones as potassium channel openers | KCNJ2, KCNJ11, KCNH1 | TTR 2975/4885MEN1 773/4885KMT2A 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.