Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL6171686 | 0.88 | ALDH1A1 (0.47) | — | |
| Tetrahydrofuran SCHEMBL9067165 | 0.88 | ALDH1A1 (0.47) | — | |
| SCHEMBL4558578 | 0.88 | — | — | |
| SCHEMBL3423848 | 0.85 | ALDH1A1 (0.44) | — | |
| SCHEMBL28247936 | 0.85 | ALDH1A1 (0.44) | — | |
| Fluoride SCHEMBL27878776 | 0.82 | — | — | |
| SCHEMBL5306546 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL1153 | 0.78 | — | — | |
| SCHEMBL11615697 | 0.78 | — | — | |
| Dioxane SCHEMBL6985191 | 0.76 | TTR (0.43) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403776-B1 | TREATING ANTIBIOTIC COMPOUND WITH NUCLEOPHILE TO CLEAVE PROTECTING GROUP FROM HYDROXYL GROUP | PFIZER INC. | 2002-06-11 | — | — | US | claimed |
| US-6290926-B1 | CATALYSIS OF CARBON MONOXIDE CONVERSION VIA THE WATER-GAS SHIFT REACTION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2001-09-18 | — | — | US | claimed |
| US-4900477-A | Novel intermediates and an improved process for producing the compound (3β,5α)-3-hydroxycholest-8(14)-en-15-one | AMERICAN CYANAMID COMPANY (US) | 1990-02-13 | — | — | US | claimed |
| US-10351540-B2 | 1,2-dithiolane and dithiol compounds useful in treating mutant EGFR-mediated diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-20180208564-A1 | 1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS | SABILA BIOSCIENCES LLC (US) | 2018-07-26 | — | — | US | disclosed |
| US-8642497-B2 | Processes for the preparation of tetrakis(Faryl)borate salts | ALBEMARLE CORPORATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-7589105-B2 | For example, N,N'-bis(3-hydroxyphenyl)pyrimidine-4,6-diamine, 2-methyl-N,N'-bis(3-hydroxyphenyl)pyrimidine-4,6-diamine | BTG INTERNATIONAL LIMITED (GB) | 2009-09-15 | — | — | US | disclosed |
| US-20080306302-A1 | Processes for the Preparation of Tetrakis(F Aryl)Borate Salts | W. R. GRACE & CO-CONN. | 2008-12-11 | — | — | US | disclosed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
| US-7256211-B1 | 8-azaprostaglandin derivatives and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| WO-2007037540-A1 | CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, OPTICALLY COMPENSATORY FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |
| WO-1998052915-A2 | LEUKOTRIENE B4 DERIVATIVES, IN PARTICULAR OXIMO-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |
| WO-1998052916-A1 | NOVEL LEUKOTRIENE-B DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |
| US-5545744-A | Cyano naphthalene compounds | AGOURON PHARMACEUTICALS, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5498727-A | Preparation of benzindole compounds from naphthalene compounds | AGOURON PHARMACEUTICALS, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1996002502-A1 | PREPARATION OF BENZINDOLE COMPOUNDS FROM NAPHTHALENE COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-02-01 | — | — | WO | disclosed |
| US-4940804-A | MACROLACTONE ANTIBIOTICS | GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (US) | 1990-07-10 | — | — | US | disclosed |
| US-4144249-A | 2,2,6,6-TETRAMETHYL-BENZOBISDIOXOLE, USEFUL IN PERFUMES | S.A. TEXACO BELGIUM N.V. (BE) | 1979-03-13 | — | — | US | disclosed |
| EP-0000800-A1 | Selective N-protection of aminoglycosides and novel, selectively protected aminoglycoside intermediates | Technobiotic Ltd. (CH) | 1979-02-21 | — | — | EP | disclosed |
| US-4092331-A | FROM A POLYHYDRIC PHENOL CONTAINING TWO PAIR ORTHO HYDROXY GROUPS AND A KETONE OR ACETAL, LEWIS ACID CATALYST | S.A. TEXACO BELGIUM N.V. (BE) | 1978-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208564-A1 | 1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS | EGFR, BRCA1, PTPRJ | TTR 166/4885 |
| US-10351540-B2 | 1,2-dithiolane and dithiol compounds useful in treating mutant EGFR-mediated diseases and conditions | EGFR, BRCA1, PTPRJ | TTR 166/4885 |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | HPGDS, PTGIS, PTGER4 | TTR 4364/4885 |
| US-20080306302-A1 | Processes for the Preparation of Tetrakis(F Aryl)Borate Salts | NBAS, TBCB, TBC1D15 | TTR 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.