Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986357 | 0.90 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL6986217 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL680660 | 0.77 | CALM1 (0.71) | CALM1ALDH1A1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL28546549 | 0.76 | CA2 (0.61) | ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL8867447 | 0.74 | CALM1 (0.67) | CALM1ALDH1A1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL3938308 | 0.74 | CALM1 (0.67) | CALM1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL1251843 | 0.74 | KDM4E (0.77) | CALM1CYP1A2CYP3A4MAPTATM | |
| SCHEMBL11044914 | 0.74 | CALM1 (0.67) | CALM1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL5873476 | 0.74 | CALM1 (0.67) | CALM1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL29543507 | 0.74 | KDM4E (0.77) | CALM1CYP1A2CYP3A4MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |