Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247762 | 0.89 | MAPT (0.46) | KMT2ANPC1RAB9ATYRDRD3 | |
| SCHEMBL25849475 | 0.87 | MAPT (0.47) | KMT2ANPC1RAB9ADRD3MAPT | |
| SCHEMBL23374492 | 0.85 | MAPT (0.46) | KMT2ANPC1RAB9ADRD3MEN1 | |
| SCHEMBL252411 | 0.83 | KMT2A (0.41) | KMT2ANPC1RAB9ADRD3MEN1 | |
| SCHEMBL3860760 | 0.82 | KMT2A (0.40) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL13896708 | 0.80 | DRD3 (0.39) | KMT2ANPC1RAB9ADRD3MEN1 | |
| SCHEMBL589545 | 0.80 | KMT2A (0.40) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL588860 | 0.80 | KMT2A (0.43) | KMT2ANPC1RAB9ATYRMEN1 | |
| SCHEMBL5196773 | 0.79 | ACVRL1 (0.41) | KMT2ANPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL1915950 | 0.79 | KMT2A (0.40) | KMT2ANPC1RAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-4185584-A1 | SREBP INHIBITORS COMPRISING A THIOPHENE CENTRAL RING | Capulus Therapeutics, LLC (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20230119547-A1 | DI-SUBSTITUTED PYRAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES | FGH BIOTECH INC (US) | 2023-04-20 | — | — | US | disclosed |
| US-11497738-B2 | Di-substituted pyrazole compounds for the treatment of diseases | FGH BIOTECH, INC. (US) | 2022-11-15 | — | — | US | disclosed |
| CN-110072861-B | Disubstituted pyrazoles for the treatment of diseases | FGH生物科技公司 | 2022-11-11 | — | — | CN | disclosed |
| EP-3510027-B1 | DI-SUBSTITUTED PYRAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES | FGH BIOTECH INC (US) | 2022-11-02 | — | — | EP | disclosed |
| US-11339142-B2 | Di-substituted pyrazole compounds for the treatment of diseases | FGH BIOTECH, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| EP-3448851-B1 | DI-SUBSTITUTED PYRAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES | FGH BIOTECH INC (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-109476635-B | Disubstituted pyrazoles for treatment of diseases | FGH生物科技公司 | 2021-07-13 | — | — | CN | disclosed |
| EP-2906539-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014057103-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2014-04-17 | — | — | WO | disclosed |
| WO-2014057103-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2014-04-17 | — | — | WO | disclosed |
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1087967-B1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| CN-1305476-A | 1,3-oxazoline and 1,3-thiazoline derivatives, method for producing the same and their use as pesticides | AVENTIS CORP SCIENCE GMBH (DE) | 2001-07-25 | — | — | CN | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1087967-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065901-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339142-B2 | Di-substituted pyrazole compounds for the treatment of diseases | SREBF1, SREBF2, CYP27A1 | KMT2A 3519/4885NPC1 74/4885RAB9A 1340/4885 |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | KMT2A 2461/4885NPC1 3642/4885RAB9A 4145/4885 |
| US-20230119547-A1 | DI-SUBSTITUTED PYRAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES | SREBF1, SREBF2, CYP27A1 | KMT2A 3519/4885NPC1 74/4885RAB9A 1340/4885 |
| US-11497738-B2 | Di-substituted pyrazole compounds for the treatment of diseases | SREBF1, SREBF2, CYP27A1 | KMT2A 3519/4885NPC1 74/4885RAB9A 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.