Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513096 | 0.98 | CCR2 (0.41) | CCR2ALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL28513095 | 0.98 | CCR2 (0.41) | CCR2ALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL4977283 | 0.93 | L3MBTL1 (0.42) | CCR2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28399036 | 0.93 | L3MBTL1 (0.42) | CCR2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28830363 | 0.85 | L3MBTL1 (0.33) | CCR2L3MBTL1 | |
| SCHEMBL28830362 | 0.85 | L3MBTL1 (0.33) | CCR2L3MBTL1 | |
| SCHEMBL27891475 | 0.82 | CCR2 (0.46) | CCR2L3MBTL1RAB9ANPC1 | |
| SCHEMBL17817926 | 0.77 | L3MBTL1 (0.43) | CCR2ALDH1A1L3MBTL1 | |
| SCHEMBL9710391 | 0.77 | L3MBTL1 (0.43) | CCR2ALDH1A1L3MBTL1 | |
| SCHEMBL17817921 | 0.77 | L3MBTL1 (0.43) | CCR2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |