Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830363 | 1.00 | L3MBTL1 (0.33) | L3MBTL1MAP4K1CCR2KLK5 | |
| SCHEMBL28399036 | 0.89 | L3MBTL1 (0.42) | L3MBTL1CCR2KLK5 | |
| SCHEMBL4977283 | 0.89 | L3MBTL1 (0.42) | L3MBTL1CCR2KLK5 | |
| SCHEMBL28513095 | 0.87 | CCR2 (0.41) | L3MBTL1CCR2KLK5 | |
| SCHEMBL28513096 | 0.87 | CCR2 (0.41) | L3MBTL1CCR2KLK5 | |
| SCHEMBL6985316 | 0.85 | CCR2 (0.44) | L3MBTL1CCR2 | |
| SCHEMBL1426470 | 0.82 | L3MBTL1 (0.34) | L3MBTL1MAP4K1CCR2 | |
| SCHEMBL11084174 | 0.82 | POLB (0.35) | L3MBTL1MAP4K1CCR2 | |
| SCHEMBL11084177 | 0.82 | POLB (0.35) | L3MBTL1MAP4K1CCR2 | |
| SCHEMBL11084182 | 0.82 | POLB (0.35) | L3MBTL1MAP4K1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845711-A | Inhibitors of RAF kinase | 金耐特生物制药公司 | 2022-08-02 | — | — | CN | disclosed |