Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223925 | 0.93 | KMT2A (0.38) | SQORMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL5227509 | 0.76 | MAPT (0.55) | MAPTKDM4EKMT2ANPSR1ALDH1A1 | |
| SCHEMBL5221810 | 0.76 | ALDH1A1 (0.46) | MAPTKDM4EKMT2ANPSR1ALDH1A1 | |
| SCHEMBL5223501 | 0.74 | TRPA1 (0.44) | SQORMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL5229089 | 0.73 | NPC1 (0.44) | MAPTKDM4EKMT2ANPSR1ALDH1A1 | |
| SCHEMBL5222944 | 0.72 | ALDH1A1 (0.40) | MAPTKDM4EKMT2ANPSR1ALDH1A1 | |
| SCHEMBL10971380 | 0.72 | MAPK14 (0.54) | MAPK14GCGRMAPK13ALOX5MAPK12 | |
| SCHEMBL5223530 | 0.72 | MAPK14 (0.46) | MAPTKDM4EKMT2ANPSR1ALDH1A1 | |
| SCHEMBL5221631 | 0.72 | SYK (0.42) | SQORMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL5226799 | 0.71 | SYK (0.44) | MAPTKDM4EKMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |