Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224315 | 0.90 | L3MBTL1 (0.44) | ALDH1A1LMNAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL5222944 | 0.83 | ALDH1A1 (0.40) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5225080 | 0.82 | NPSR1 (0.50) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5227509 | 0.81 | MAPT (0.55) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5227004 | 0.78 | NPC1 (0.62) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6985387 | 0.76 | SQOR (0.39) | ALDH1A1NPSR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5221958 | 0.75 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5223322 | 0.74 | BTK (0.50) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5224304 | 0.73 | ADORA1 (0.53) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5222119 | 0.71 | KMT2A (0.44) | ALDH1A1NPSR1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |