Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976980 | 0.82 | TP53 (0.41) | HSD17B10ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL7532436 | 0.80 | HPGD (0.50) | ALDH1A1TDP1L3MBTL1ALOX15ALOX12 | |
| SCHEMBL28874218 | 0.80 | NPC1 (0.47) | HSD17B10ALDH1A1TDP1L3MBTL1MAPK1 | |
| SCHEMBL28833087 | 0.80 | SMN1; SMN2 (0.51) | HSD17B10ALDH1A1L3MBTL1ALOX15ALOX12 | |
| SCHEMBL7532433 | 0.80 | AKT1 (0.36) | HSD17B10ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL28304722 | 0.80 | RAB9A (0.47) | HSD17B10ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL30416990 | 0.76 | NPSR1 (0.55) | HSD17B10ALDH1A1MAPK1MAPTKMT2A | |
| SCHEMBL29068394 | 0.72 | HSD17B10 (0.58) | HSD17B10ALDH1A1TDP1L3MBTL1ALOX15 | |
| Diphenylamine SCHEMBL27854338 | 0.72 | HSD17B10 (0.67) | HSD17B10ALDH1A1TDP1L3MBTL1ALOX15 | |
| Diphenylamine SCHEMBL28271708 | 0.70 | HSD17B10 (0.86) | HSD17B10ALDH1A1TDP1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440390-A | Substituted diamine derivatives as motilin antagonists | ORTHO MCNEIL PHARM INC (US) | 2003-09-03 | — | — | CN | claimed |
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | claimed |
| CN-111354873-B | Compound for organic electric element, organic electric element using same, and electronic device using same | 德山新勒克斯有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116640159-A | Light-emitting element and polycyclic compound for light-emitting element | 三星显示有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116017996-A | Light-emitting element | 三星显示有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022183900-A1 | ORGANIC LIGHT-EMITTING DEVICE HAVING THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL AS LIGHT-EMITTING LAYER MATERIAL | 北京大学深圳研究生院 | 2022-09-09 | — | — | WO | disclosed |
| CN-114641870-A | Organic electric element comprising a plurality of luminescence auxiliary layers and electronic device comprising same | 德山新勒克斯有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-113150192-B | Chiral helix-loaded aromatic amide type resin and preparation method and application thereof | 华中科技大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-113845538-A | Furan-fused boron-nitrogen heterodihydropyrene and synthetic method thereof | 天津理工大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-113150192-A | Chiral helix-loaded aromatic amide type resin and preparation method and application thereof | 华中科技大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-109928893-A | A kind of α-Process for the cyanation of N- arylmethyl aniline | 重庆大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-107880055-A | A kind of blue-fluorescence dopant and the organic electroluminescence device comprising this material | 南京高光半导体材料有限公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-103130594-A | Method preparing N-aryl and N-alkyl aromatic amine type compound from phenol type compound | UNIV ZHEJIANG | 2013-06-05 | — | — | CN | disclosed |
| CN-100526980-C | Lithographic printing plate precursor and lithographic printing method | FUJI PHOTO FILM CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
| CN-1577087-A | Lithographic printing plate precursor and lithographic printing method | FUJI PHOTO FILM CO LTD (JP) | 2005-02-09 | — | — | CN | disclosed |
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | disclosed |