Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985407 | 0.80 | HSD17B10 (0.50) | MAPTSMN1; SMN2TP53MEN1NPC1 | |
| SCHEMBL28833087 | 0.79 | SMN1; SMN2 (0.51) | AKT1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL28304722 | 0.79 | RAB9A (0.47) | AKT1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL28874218 | 0.79 | NPC1 (0.47) | AKT1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL7532436 | 0.79 | HPGD (0.50) | AKT1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL976980 | 0.77 | TP53 (0.41) | AKT1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL10644016 | 0.69 | — | — | |
| SCHEMBL30925347 | 0.68 | ADRA2C (0.50) | MAPTSMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL4781334 | 0.67 | ALDH1A1 (0.72) | MAPTSMN1; SMN2MEN1GFERKMT2A | |
| SCHEMBL2845839 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |