Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643872 | 0.82 | RAB9A (0.40) | HPGDGSK3BGAAPOLBSMN1; SMN2 | |
| SCHEMBL6985407 | 0.80 | HSD17B10 (0.50) | HPGDGAASMN1; SMN2MAPTTDP1 | |
| SCHEMBL7532433 | 0.79 | AKT1 (0.36) | GSK3BGAASMN1; SMN2MAPTTDP1 | |
| SCHEMBL28833087 | 0.79 | SMN1; SMN2 (0.51) | HPGDGAASMN1; SMN2MAPTRAB9A | |
| SCHEMBL28874218 | 0.79 | NPC1 (0.47) | HPGDPOLBSMN1; SMN2MAPTTDP1 | |
| SCHEMBL28304722 | 0.79 | RAB9A (0.47) | HPGDGAAPOLBSMN1; SMN2MAPT | |
| SCHEMBL30416990 | 0.79 | NPSR1 (0.55) | HPGDGAAPOLBSMN1; SMN2MAPT | |
| SCHEMBL976980 | 0.77 | TP53 (0.41) | HPGDPOLBSMN1; SMN2MAPTTDP1 | |
| SCHEMBL30925347 | 0.71 | ADRA2C (0.50) | GAASMN1; SMN2MAPTTDP1RAB9A | |
| SCHEMBL108881 | 0.71 | HPGD (0.78) | HPGDGAASMN1; SMN2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |
| CN-110054631-A | Bromo- 4- chlorine furans [2,3-b] quinoline of 2-, derivative and synthetic method and application | 中国药科大学 | 2019-07-26 | — | — | CN | disclosed |