Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985716 | 0.70 | CHRNB2 (0.37) | CHRNB2CHRNA4NFE2L2MAPT | |
| SCHEMBL24687082 | 0.69 | NQO1 (0.54) | CHRNB2CHRNA4NFE2L2 | |
| SCHEMBL115868 | 0.65 | — | — | |
| SCHEMBL29413312 | 0.65 | — | — | |
| SCHEMBL6985714 | 0.64 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL6985718 | 0.64 | ALDH1A1 (0.35) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL5173871 | 0.64 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL5175410 | 0.64 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL595487 | 0.63 | CHRNB2 (0.44) | CHRNB2CHRNA4NFE2L2 | |
| SCHEMBL29965553 | 0.63 | CHRNB2 (0.44) | CHRNB2CHRNA4NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313704-A2 | COMPOUNDS USEFUL AS INSECTICIDES, COMPOUNDS USEFUL AS ACARICIDES, AND PROCESSES TO USE AND MAKE SAME | Dow AgroSciences LLC (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018339-A2 | COMPOUNDS USEFUL AS INSECTICIDES, COMPOUNDS USEFUL AS ACARICIDES, AND PROCESSES TO USE AND MAKE SAME | DOW AGROSCIENCES LLC (US) | 2002-03-07 | — | — | WO | disclosed |