Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648779 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BCA2CYP2A6KEAP1 | |
| SCHEMBL5234280 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BCA2CYP2A6MAPT | |
| SCHEMBL8435459 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BCA2CYP2A6MAPT | |
| SCHEMBL7146984 | 0.83 | CA2 (0.55) | MTNR1AMTNR1BCA2CYP2A6KEAP1 | |
| SCHEMBL2094883 | 0.81 | MTNR1A (0.52) | MTNR1AMTNR1BCA2CYP2A6KEAP1 | |
| SCHEMBL8586113 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1BCA2CYP2A6MAPT | |
| SCHEMBL27628031 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1BCA2CYP2A6KEAP1 | |
| SCHEMBL8435339 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BCA2CYP2A6MAPT | |
| Hydrochloric Acid SCHEMBL7145521 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BCA2CYP2A6MAPT | |
| SCHEMBL15810200 | 0.76 | MTNR1A (0.57) | MTNR1AMTNR1BCA2CYP2A6KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044170-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2002-06-06 | — | — | WO | disclosed |