Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958935 | 0.92 | F10 (0.41) | NR3C1POLBPDK1PDK2PDK3 | |
| SCHEMBL6982322 | 0.90 | NR3C1 (0.47) | NR3C1POLBALDH1A1F2HPGD | |
| SCHEMBL6979171 | 0.90 | USP2 (0.41) | NR3C1USP2MAPK1POLBLMNA | |
| Iodide SCHEMBL7960633 | 0.90 | F2 (0.41) | NR3C1POLBPDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL6979622 | 0.89 | F2 (0.39) | NR3C1POLBPDK1PDK2PDK3 | |
| SCHEMBL6987763 | 0.88 | NR3C1 (0.47) | NR3C1USP2MAPK1POLBLMNA | |
| SCHEMBL7405916 | 0.87 | NR3C1 (0.46) | NR3C1POLBLMNAPDK1PDK2 | |
| Hydrochloric Acid SCHEMBL6984704 | 0.86 | NR3C1 (0.49) | NR3C1POLBLMNAGAAALDH1A1 | |
| SCHEMBL6979175 | 0.86 | USP2 (0.39) | NR3C1USP2MAPK1POLBLMNA | |
| Iodide SCHEMBL7949045 | 0.86 | NR3C1 (0.46) | NR3C1POLBLMNAPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |