Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985778 | 0.88 | NR3C1 (0.43) | NR3C1USP2MAPK1POLBGAA | |
| SCHEMBL6980127 | 0.87 | NR3C1 (0.53) | NR3C1POLBKDM1AGAALMNA | |
| SCHEMBL6985993 | 0.87 | NR3C1 (0.46) | NR3C1MAPK1POLBKDM1AGAA | |
| SCHEMBL6979171 | 0.86 | USP2 (0.41) | NR3C1USP2MAPK1POLBGAA | |
| SCHEMBL6987767 | 0.86 | TP53 (0.42) | NR3C1USP2KDM1AGAALMNA | |
| SCHEMBL6982684 | 0.85 | KDM1A (0.43) | NR3C1USP2MAPK1KDM1ALMNA | |
| SCHEMBL6977634 | 0.85 | NR3C1 (0.53) | NR3C1USP2MAPK1LMNAMAPT | |
| SCHEMBL7407618 | 0.85 | ALDH1A1 (0.44) | NR3C1MAPK1KDM1AGAAMAPT | |
| SCHEMBL7958945 | 0.85 | PDK1 (0.41) | NR3C1USP2MAPK1GAAMAPT | |
| SCHEMBL6982826 | 0.84 | P2RX7 (0.41) | NR3C1KDM1AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |