Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984846 | 0.91 | USP2 (0.38) | USP2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6980895 | 0.89 | PDK1 (0.40) | USP2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6984481 | 0.87 | F2 (0.41) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL6978636 | 0.87 | PDK1 (0.36) | USP2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6985778 | 0.86 | NR3C1 (0.43) | USP2PDK1PDK2PDK3PDK4 | |
| SCHEMBL7089640 | 0.85 | PDK1 (0.36) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL7960545 | 0.83 | F2 (0.44) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL6979171 | 0.83 | USP2 (0.41) | USP2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6981264 | 0.81 | NR3C1 (0.48) | POLBLMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL6978188 | 0.80 | LMNA (0.54) | USP2LMNAALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |