SCHEMBL69859

SCHEMBL69859

Oc1cccc(Oc2ccccc2O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.46
AR P10275 1/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
TTR P02766 2/20 0.44
CYP3A4 P08684 2/20 0.44
CA2 P00918 2/20 0.43
CA1 P00915 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CA12 O43570 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14332272 0.96 F2 (0.44) F2ARTHRATHRBTTR
SCHEMBL8969033 0.90 AR (0.49) ARTHRATHRBTTRCYP3A4
SCHEMBL8693307 0.90 CYP3A4 (0.48) F2THRATHRBCYP3A4CA2
SCHEMBL10797392 0.87 NR1H2 (0.42) F2ARTHRATHRBTTR
1-Hydroxy-3-Methoxybenzene SCHEMBL6420591 0.86 TSHR (0.48) TTRCA2CA1TP53TSHR
SCHEMBL11826075 0.86 LTA4H (0.50) F2TTRCYP3A4CA2TSHR
Resorcinol SCHEMBL17200868 0.85 CA2 (0.55) F2TTRCYP3A4CA2CA1
SCHEMBL11157060 0.84 F2 (0.54) F2THRATHRBCYP3A4CA2
SCHEMBL9588301 0.84 TTR (0.53) ARTTRCA2CA1TP53
SCHEMBL8653193 0.84 CYP3A4 (0.44) F2THRATHRBCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160146801-A1 NOVEL BIOMARKER DETECTION WITH MOLECULAR IMPRINTS UNIVERSITY OF HOUSTON SYSTEM 2016-05-26 US disclosed
CN-103906610-B For the drying fiber material that follow-up resin pours into CYTEC INDUSTRIES INC. (US) 2016-03-30 CN disclosed
US-8901072-B2 Glycopeptide and lipoglycopeptide antibiotics with improved solubility THE MEDICINES COMPANY (US) 2014-12-02 US disclosed
CN-103906610-A Dry fibrous material for subsequent resin infusion CYTEC IND INC 2014-07-02 CN disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4180665-A Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-25 US disclosed
EP-0005858-A1 Preparation of polyarylates UNION CARBIDE CORPORATION (US) 1979-12-12 EP disclosed
US-4174457-A Carbamate UNIROYAL, INC. (US) 1979-11-13 US disclosed
US-4159379-A Dispersion dyestuffs of the naphtholactam series CIBA-GEIGY AG (CH) 1979-06-26 US disclosed
US-4148805-A POLYESTERS, RED, YELLLOW CIBA-GEIGY AG (CH) 1979-04-10 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed
US-4080408-A FIRE RETARDANTS UNIROYAL, INC. (US) 1978-03-21 US disclosed
US-4058568-A FIRE RETARDANT UNIROYAL, INC. (US) 1977-11-15 US disclosed
US-4009200-A FIREPROOFING POLYMERS UNIROYAL, INC. (US) 1977-02-22 US disclosed
US-3933957-A Process for producing shaped articles from an acetylenic polymer GENERAL ELECTRIC COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 F2 1398/4885AR 68/4885THRA 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.