SCHEMBL8969033

SCHEMBL8969033

Oc1ccccc1Oc1cccc(Oc2ccccc2O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.49
TTR P02766 2/20 0.48
TP53 P04637 3/20 0.48
TSHR P16473 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MAPT P10636 4/20 0.45
GAA P10253 3/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MITF O75030 1/20 0.45
GFER P55789 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NLRP1 Q9C000 1/20 0.45
NOD2 Q9HC29 1/20 0.45
JAK2 O60674 1/20 0.45
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588301 0.94 TTR (0.53) ARTTRTP53TSHRCA1
SCHEMBL69859 0.90 F2 (0.46) ARTTRTP53TSHRCA1
SCHEMBL14332272 0.86 F2 (0.44) ARTTRTP53TSHRCA1
SCHEMBL3174031 0.86 ALDH1A1 (0.64) ARTP53TSHRCA1CA2
SCHEMBL4338407 0.86 SLC6A4 (0.50) ARTTRTP53TSHRCA1
SCHEMBL7035780 0.86 THRA (0.50) ARTTRTP53TSHRCA1
SCHEMBL30979267 0.86 ALDH1A1 (0.64) ARTP53TSHRCA1CA2
SCHEMBL4348260 0.86 SLC6A4 (0.54) ARTTRMAPTALDH1A1LMNA
SCHEMBL29449754 0.86 TTR (0.57) TTRTP53TSHRCA1CA2
SCHEMBL260447 0.86 TTR (0.57) TTRTP53TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699216-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-06 EP disclosed
WO-1994028052-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-08 WO disclosed
US-5288835-A 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US disclosed