Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 16/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399325 | 0.90 | CASR (0.55) | CASRMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4397215 | 0.89 | CASR (0.55) | CASRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6989540 | 0.89 | CASR (0.49) | CASRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6988739 | 0.88 | CASR (0.62) | CASR | |
| SCHEMBL4391833 | 0.88 | CASR (0.43) | CASRMEN1KMT2AALDH1A1 | |
| SCHEMBL6985526 | 0.85 | ALDH1A1 (0.46) | CASRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4562924 | 0.83 | CASR (0.47) | CASRMEN1KMT2A | |
| SCHEMBL4543747 | 0.82 | CASR (0.53) | CASRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4551042 | 0.81 | CASR (0.53) | CASRMEN1KMT2A | |
| SCHEMBL4401060 | 0.80 | CASR (0.47) | CASRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358171-A2 | NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE | Aventis Pharma S.A. (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059102-A2 | UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE | AVENTIS PHARMA S.A. (FR) | 2002-08-01 | — | — | WO | disclosed |