Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989540 | 0.93 | CASR (0.49) | ALDH1A1MAPTGAACASRMEN1 | |
| SCHEMBL4403137 | 0.89 | LMNA (0.48) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4402106 | 0.88 | CASR (0.50) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL6988739 | 0.87 | CASR (0.62) | CASR | |
| SCHEMBL6986096 | 0.85 | CASR (0.49) | ALDH1A1GAACASRMEN1KMT2A | |
| SCHEMBL4401060 | 0.83 | CASR (0.47) | ALDH1A1LMNAMAPTGAACASR | |
| SCHEMBL4394593 | 0.82 | CASR (0.53) | ALDH1A1GAACASRNPY5R | |
| SCHEMBL7092061 | 0.82 | CCR5 (0.47) | CASR | |
| SCHEMBL4391778 | 0.81 | CASR (0.51) | LMNAGAASMN1; SMN2CASR | |
| Hydrochloric Acid SCHEMBL4391804 | 0.81 | CASR (0.53) | ALDH1A1GAACASRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358171-A2 | NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE | Aventis Pharma S.A. (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059102-A2 | UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE | AVENTIS PHARMA S.A. (FR) | 2002-08-01 | — | — | WO | disclosed |