Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985526 | 0.93 | ALDH1A1 (0.46) | CASRALDH1A1GAAFAAHMEN1 | |
| SCHEMBL6988739 | 0.91 | CASR (0.62) | CASR | |
| SCHEMBL4401060 | 0.90 | CASR (0.47) | CASRALDH1A1GAAKCNA5HTT | |
| SCHEMBL4394593 | 0.90 | CASR (0.53) | CASRALDH1A1GAAKCNA5SLC1A2 | |
| SCHEMBL6986096 | 0.89 | CASR (0.49) | CASRALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4391804 | 0.89 | CASR (0.53) | CASRALDH1A1GAAKCNA5SLC1A2 | |
| Hydrochloric Acid SCHEMBL4403194 | 0.86 | CASR (0.50) | CASRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4403137 | 0.84 | LMNA (0.48) | CASRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7092061 | 0.82 | CCR5 (0.47) | CASR | |
| SCHEMBL4391778 | 0.82 | CASR (0.51) | CASRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358171-A2 | NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE | Aventis Pharma S.A. (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059102-A2 | UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE | AVENTIS PHARMA S.A. (FR) | 2002-08-01 | — | — | WO | disclosed |