Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651011 | 0.89 | DHFR (0.36) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL6986832 | 0.87 | HSD11B1 (0.35) | ALDH1A1DHFR | |
| SCHEMBL13651003 | 0.83 | NSD2 (0.36) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6987417 | 0.72 | MAPT (0.54) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL6983548 | 0.68 | NOS3 (0.51) | — | |
| SCHEMBL29428410 | 0.67 | MAPT (1.00) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL998182 | 0.67 | MAPT (1.00) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL12880138 | 0.66 | MAPT (0.75) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL29512056 | 0.66 | MAPT (0.75) | MAPTMEN1KMT2ANISCHALDH1A1 | |
| SCHEMBL6986785 | 0.65 | NOS3 (0.46) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183378-B2 | Ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-05-22 | — | — | US | disclosed |