Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302 | 0.81 | POLB (0.44) | L3MBTL1DAOIDO1MAOBALDH1A1 | |
| SCHEMBL8991864 | 0.78 | MAPK1 (0.47) | L3MBTL1DAODRD2MAOBALDH1A1 | |
| SCHEMBL4807017 | 0.75 | ALDH1A1 (0.40) | MAPTIDO1MAOBALDH1A1TAAR1 | |
| SCHEMBL13319914 | 0.74 | MAPT (0.58) | MAPTL3MBTL1ALOX15BDAOIDO1 | |
| Ammonia Solution, Strong SCHEMBL6900996 | 0.73 | MAPT (0.57) | MAPTL3MBTL1ALOX15BDAOIDO1 | |
| SCHEMBL6715685 | 0.72 | — | — | |
| SCHEMBL8995181 | 0.71 | — | — | |
| SCHEMBL3889144 | 0.70 | MAPT (0.54) | MAPTL3MBTL1ALOX15BDAOIDO1 | |
| SCHEMBL13319587 | 0.70 | MAPT (0.53) | MAPTL3MBTL1ALOX15BIDO1MAOB | |
| SCHEMBL1982483 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |