Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302 | 0.85 | POLB (0.44) | ALDH1A1NPC1RAB9ADAOL3MBTL1 | |
| SCHEMBL6986464 | 0.78 | MAPT (0.51) | ALDH1A1DRD2DAOL3MBTL1MAOB | |
| SCHEMBL2125462 | 0.78 | TP53 (0.33) | — | |
| SCHEMBL1196530 | 0.75 | L3MBTL1 (0.40) | MAPK1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8995181 | 0.75 | — | — | |
| SCHEMBL28847125 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3080439 | 0.73 | TP53 (0.30) | — | |
| SCHEMBL7311317 | 0.72 | — | — | |
| SCHEMBL19746445 | 0.72 | TAAR1 (0.35) | DRD2 | |
| SCHEMBL1531966 | 0.72 | SIGMAR1 (0.37) | MEN1KMT2AALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719771-A1 | Process for the preparation of methylene compounds and the compound 2-(2',4'-dichloro-5'-fluorobenzyl)-thiophene | BAYER AG (DE) | 1996-07-03 | — | — | EP | disclosed |