SCHEMBL4302

SCHEMBL4302

[c]1ccccc1SCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RAB9A P51151 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
NPC1 O15118 2/20 0.39
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
PRMT1 Q99873 1/20 0.37
S100A4 P26447 1/20 0.37
DAO P14920 1/20 0.37
IDO1 P14902 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991864 0.85 MAPK1 (0.47) RAB9ASMN1; SMN2MAOAMAOBNPC1
SCHEMBL2199347 0.82 CYP1A2 (0.43) HSD17B10RAB9ASMN1; SMN2MAOAMAOB
SCHEMBL8995181 0.81
SCHEMBL6986464 0.81 MAPT (0.51) MAOBDAOIDO1ALDH1A1L3MBTL1
SCHEMBL19746445 0.78 TAAR1 (0.35) POLB
SCHEMBL997130 0.76 POLB (0.41) POLBHSD17B10RAB9ASMN1; SMN2MAOA
SCHEMBL3084401 0.76 TP53 (0.36) RAB9ASMN1; SMN2NPC1CYP1A2CYP3A4
SCHEMBL28847125 0.76 L3MBTL1 (0.40) POLBHSD17B10RAB9ASMN1; SMN2MAOA
SCHEMBL9934897 0.75 ALDH1A1 (0.39) POLBSMN1; SMN2CYP1A2CYP3A4ALDH1A1
SCHEMBL3072382 0.75 LMNA (0.35) POLBRAB9ASMN1; SMN2NPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 84328 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043634-B2 Metal complexes, methods of making the same, and uses thereof THE UNIVERSITY OF MANITOBA (CA) 2024-07-23 US claimed
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US claimed
WO-2024149340-A1 INDOLONE DERIVATIVE HAVING IRAK4 INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳众格生物科技有限公司 2024-07-18 WO claimed
US-20240239824-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US claimed
US-20240244953-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US claimed
CN-111864121-B Organic light emitting device 三星显示有限公司 2024-07-16 CN claimed
CN-118324771-A Organic light-emitting device, electronic device, and heterocyclic compound 三星显示有限公司 2024-07-12 CN claimed
US-20240228472-A1 HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-11 US claimed
US-20240228456-A1 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2024-07-11 US claimed
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-11 US claimed
EP-0241395-A2 Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) 1987-10-14 EP claimed
EP-0236913-A2 Aryl-azolylmethyl-benzocyclo-alkene derivatives, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-16 EP claimed
US-4571406-A Anti-hypertensive chromans and chromenes BEECHAM GROUP P.L.C. (GB) 1986-02-18 US claimed
US-4555579-A Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitors E. R. SQUIBB & SONS, INC. (US) 1985-11-26 US claimed
EP-0035374-B1 PIPERIDYL - UREA, - THIOUREA AND - GUANIDINE DERIVATIVES, AND INTERMEDIATES THEREFOR, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES JOHN WYETH & BROTHER LIMITED (GB) 1985-01-30 EP claimed
EP-0126311-A2 Benzopyran derivatives. BEECHAM GROUP PLC (GB) 1984-11-28 EP claimed
EP-0035374-A2 Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives JOHN WYETH & BROTHER LIMITED (GB) 1981-09-09 EP claimed
US-3994724-A SUBSTITUTED ANILINE PHOTOCONDUCTOR SCOTT PAPER COMPANY (US) 1976-11-30 US claimed
US-3993645-A Stilbene optical brighteners and compositions brightened therewith STERLING DRUG INC. (US) 1976-11-23 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed