Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841577 | 0.80 | NOS2 (0.47) | BRS3TAAR1MAPKAPK2SLC6A2SLC6A4 | |
| SCHEMBL6714998 | 0.79 | MAPKAPK2 (0.46) | MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL7845559 | 0.74 | NOS2 (0.43) | BRS3MAPKAPK2HRH3GRIN1GRIN2B | |
| SCHEMBL7919393 | 0.73 | BRS3 (0.62) | BRS3HRH3GRIN1GRIN2BCYP19A1 | |
| Hydrochloric Acid SCHEMBL8521500 | 0.72 | BRS3 (0.61) | BRS3HRH3GRIN1GRIN2BCYP19A1 | |
| Hydrochloric Acid SCHEMBL7936809 | 0.71 | SLC6A2 (0.46) | BRS3MAPKAPK2HRH3SLC6A2SLC6A4 | |
| SCHEMBL10588302 | 0.70 | BRS3 (0.49) | BRS3HRH3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL8498703 | 0.70 | BRS3 (0.49) | BRS3HRH3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL7129739 | 0.70 | BRS3 (0.52) | BRS3HRH3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL7505077 | 0.70 | LOXL2 (0.49) | BRS3HRH3GRIN1GRIN2BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |