Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990799 | 0.99 | HTR1A (0.54) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| SCHEMBL7050027 | 0.90 | SMN1; SMN2 (0.59) | NPY1RNAMPTNPC1MAPTRAB9A | |
| SCHEMBL7050030 | 0.90 | SMN1; SMN2 (0.59) | NPY1RNAMPTNPC1MAPTRAB9A | |
| SCHEMBL7054840 | 0.87 | NAMPT (0.52) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| SCHEMBL7090848 | 0.87 | HTR1A (0.55) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| SCHEMBL6992385 | 0.86 | NPY1R (0.55) | HTR1ADRD2NPY1RNPC1MAPT | |
| Hydrochloric Acid SCHEMBL6993221 | 0.86 | HTR1A (0.54) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| SCHEMBL6986658 | 0.85 | NPY1R (0.51) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| SCHEMBL7090266 | 0.85 | NPY1R (0.54) | HTR1ADRD2NPY1RNAMPTNPC1 | |
| Hydrochloric Acid SCHEMBL6993006 | 0.85 | NPY1R (0.54) | HTR1ADRD2NPY1RNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | claimed |