Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857357 | 0.79 | SLC6A3 (0.38) | SLC6A3HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL28814281 | 0.77 | SLC6A3 (0.36) | SLC6A3HPGDALDH1A1LMNAGAA | |
| SCHEMBL913098 | 0.76 | SMN1; SMN2 (0.36) | SLC6A3HPGDTDP1ALDH1A1LMNA | |
| SCHEMBL2233581 | 0.76 | SLC6A3 (0.38) | SLC6A3HPGDALDH1A1LMNAGAA | |
| SCHEMBL28382266 | 0.76 | ALDH1A1 (0.34) | SLC6A3TDP1ALDH1A1LMNAGAA | |
| SCHEMBL16398528 | 0.76 | ALDH1A1 (0.34) | SLC6A3TDP1ALDH1A1LMNAGAA | |
| SCHEMBL8858066 | 0.76 | ALDH1A1 (0.34) | SLC6A3TDP1ALDH1A1LMNAGAA | |
| SCHEMBL28378558 | 0.76 | CNR1 (0.37) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL629741 | 0.75 | SLC6A3 (0.37) | SLC6A3HPGDALDH1A1LMNAGAA | |
| SCHEMBL11401674 | 0.72 | SLC6A3 (0.38) | SLC6A3HPGDALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410238-B2 | Bishydroxyarylsiloxane compound and method of preparing the same | CHEIL INDUSTRIES INC. (KR) | 2013-04-02 | — | — | US | disclosed |
| EP-2423245-B1 | Bishydroxyarylsiloxane and preparation method thereof | CHEIL IND INC (KR) | 2013-03-06 | — | — | EP | disclosed |
| US-20120053316-A1 | Bishydroxyarylsiloxane Compound and Method of Preparing the Same | CHEIL INDUSTRIES INC. (KR) | 2012-03-01 | — | — | US | disclosed |
| EP-2423245-A1 | Bishydroxyarylsiloxane and preparation method thereof | Cheil Industries Inc. (KR) | 2012-02-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053316-A1 | Bishydroxyarylsiloxane Compound and Method of Preparing the Same | FHIT, SMCHD1, STS | SLC6A3 4219/4885HPGD 1305/4885TDP1 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.