Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942388 | 1.00 | GAA (0.49) | GAAMAOAMAOBMEN1KMT2A | |
| SCHEMBL1540211 | 0.87 | MAOA (0.47) | GAAMAOAMAOBMEN1KMT2A | |
| SCHEMBL19145150 | 0.87 | MAOA (0.47) | GAAMAOAMAOBMEN1KMT2A | |
| SCHEMBL1540243 | 0.84 | SIGMAR1 (0.47) | MAOAMAOBMEN1KMT2ACHRNA7 | |
| SCHEMBL2950930 | 0.83 | FKBP1A (0.47) | MAOAMAOBKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11590808 | 0.81 | MAPT (0.59) | GAAMEN1KMT2ACHRNA7L3MBTL1 | |
| SCHEMBL8267549 | 0.76 | SLC6A4 (0.56) | GAAMAOAMC4RSIGMAR1 | |
| SCHEMBL7216040 | 0.76 | SLC6A4 (0.56) | GAAMAOAMC4RSIGMAR1 | |
| SCHEMBL1619274 | 0.76 | SLC6A4 (0.56) | GAAMAOAMC4RSIGMAR1 | |
| SCHEMBL1540649 | 0.76 | FKBP1A (0.47) | MAOAMAOBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |