SCHEMBL69871

SCHEMBL69871

COC(=O)c1cocc1C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 5/20 0.45
HSD17B10 Q99714 3/20 0.45
CFTR P13569 1/20 0.45
KDM4E B2RXH2 6/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA9 Q16790 3/20 0.43
CA12 O43570 2/20 0.43
CA7 P43166 2/20 0.43
CA14 Q9ULX7 2/20 0.43
ATM Q13315 2/20 0.43
POLB P06746 2/20 0.43
PDK2 Q15119 1/20 0.43
PDK4 Q16654 1/20 0.43
GAA P10253 3/20 0.41
MAPT P10636 3/20 0.41
GLA P06280 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201394 0.91 TSHR (0.41) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL20176826 0.91 TSHR (0.41) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL9148724 0.88 MAPT (0.48) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL16289486 0.86 ALDH1A1 (0.41) TSHRLMNAALDH1A1HSD17B10CFTR
Cyclopropane SCHEMBL11656968 0.85 KDM4E (0.38) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL28737064 0.85 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10KDM4E
SCHEMBL31325743 0.84 SOS1 (0.41) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL12906724 0.84 CFTR (0.40) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL12906690 0.84 ALDH1A1 (0.52) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL16289484 0.84 TSHR (0.39) TSHRLMNAALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645721-A Preparation method of furyl high molecular weight polyamide 中科国生(杭州)科技有限公司 2024-03-05 CN claimed
CN-117510811-A Bio-based heat-resistant copolyester and preparation method and application thereof 东华大学 2024-02-06 CN claimed
CN-114478563-A Method for quickly crystallizing isosorbide 国科温州研究院(温州生物材料与工程研究所) 2022-05-13 CN claimed
CN-109666270-A Blending object and its manufacturing method 财团法人工业技术研究院 2019-04-23 CN claimed
US-20190112419-A1 BLEND AND METHOD FOR MANUFACTURING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-04-18 US claimed
US-10100440-B2 Polyester and method of manufacturing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITTUTE (TW) 2018-10-16 US claimed
US-10094050-B2 Fiber and method of manufacturing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-10-09 US claimed
US-20170121453-A1 POLYESTER AND METHOD OF MANUFACTURING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-04 US claimed
US-20170121859-A1 FIBER AND METHOD OF MANUFACTURING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-04 US claimed
US-6482946-B1 High char yield benzoxazine compositions DOW GLOBAL TECHNOLOGIES INC. 2002-11-19 US claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-119613689-A Furanyl high polymer polyester with excellent toughness and preparation method thereof 中科国生(杭州)科技有限公司 2025-03-14 CN disclosed
CN-119143704-A Preparation method for preparing five-membered ring diene compound by inverse D-A reaction 中国科学院大连化学物理研究所 2024-12-17 CN disclosed
CN-117645721-A Preparation method of furyl high molecular weight polyamide 中科国生(杭州)科技有限公司 2024-03-05 CN disclosed
WO-1991008507-A1 CHARGE TRANSFER SALTS AND USES THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-06-13 WO disclosed
EP-0431547-A2 Charge transfer salts and uses thereof International Business Machines Corporation (US) 1991-06-12 EP disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed