SCHEMBL16289486

SCHEMBL16289486

COC(=O)c1cocc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 2/20 0.39
CFTR P13569 1/20 0.39
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
NR4A2 P43354 1/20 0.39
KDM4E B2RXH2 6/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ATM Q13315 2/20 0.38
POLB P06746 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK4 Q16654 1/20 0.38
MYC P01106 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69871 0.86 TSHR (0.46) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL9148724 0.80 MAPT (0.48) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL18322304 0.79 TSHR (0.53) ALDH1A1TSHRLMNAHSD17B10MAPT
SCHEMBL201394 0.78 TSHR (0.41) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL20176826 0.78 TSHR (0.41) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL28737064 0.78 TSHR (0.52) ALDH1A1TSHRLMNAHSD17B10MAPT
SCHEMBL17978356 0.77 NR4A2 (0.40) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL31325743 0.77 SOS1 (0.41) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL12906690 0.77 ALDH1A1 (0.52) ALDH1A1TSHRLMNAHSD17B10CFTR
SCHEMBL12906724 0.77 CFTR (0.40) ALDH1A1TSHRLMNAHSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276270-A Synthesis method of compound with amido bond 湖北文理学院 2022-04-05 CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 ALDH1A1 3053/4885TSHR 507/4885LMNA 3984/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 ALDH1A1 3265/4885TSHR 235/4885LMNA 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.