Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69871 | 0.91 | TSHR (0.46) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL201394 | 0.83 | TSHR (0.41) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL9148724 | 0.80 | MAPT (0.48) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL16289486 | 0.78 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Cyclopropane SCHEMBL11656968 | 0.78 | KDM4E (0.38) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL28737064 | 0.78 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL20176830 | 0.78 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL12906690 | 0.77 | ALDH1A1 (0.52) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL31325743 | 0.77 | SOS1 (0.41) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL12906724 | 0.77 | CFTR (0.40) | TSHRLMNAALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | KRT18, NDUFS5, NDUFA5 | TSHR 3687/4885LMNA 2639/4885ALDH1A1 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.