Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988060 | 0.85 | CYP3A4 (0.41) | LMNACYP3A4ALDH1A1TDP1CYP1A2 | |
| SCHEMBL10958010 | 0.79 | CYP1A2 (0.50) | LMNACYP3A4ALDH1A1TDP1KDM4E | |
| SCHEMBL6988582 | 0.74 | CYP17A1 (0.35) | LMNACYP3A4ALDH1A1TP53MAPK1 | |
| SCHEMBL6990626 | 0.70 | CYP19A1 (0.33) | — | |
| SCHEMBL3697133 | 0.70 | ALDH1A3 (0.57) | LMNAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Bromide SCHEMBL8081397 | 0.70 | KIF11 (0.52) | ALDH1A1CYP1A2RAB9A | |
| SCHEMBL6991066 | 0.69 | CYP19A1 (0.35) | NPC1HPGDRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL8121179 | 0.68 | USP2 (0.55) | RAB9A | |
| SCHEMBL6179860 | 0.67 | SMN1; SMN2 (0.36) | LMNACYP3A4ALDH1A1TP53HPGD | |
| SCHEMBL481885 | 0.67 | MAPT (0.37) | LMNAALDH1A1MAPK1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328522-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032373-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-04-25 | — | — | WO | disclosed |