Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984041 | 0.92 | ROCK2 (0.43) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6989019 | 0.90 | FAAH (0.42) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6985205 | 0.90 | ROCK2 (0.42) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6982360 | 0.90 | HTR4 (0.42) | FAAHACHEROCK2F10HTR4 | |
| Hydrochloric Acid SCHEMBL6984317 | 0.90 | ROCK2 (0.44) | FAAHACHEROCK2F10HTR4 | |
| Hydrochloric Acid SCHEMBL6984942 | 0.90 | ROCK2 (0.42) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6985303 | 0.90 | ROCK2 (0.41) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6987886 | 0.90 | ROCK2 (0.41) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6986160 | 0.89 | ROCK2 (0.41) | FAAHACHEROCK2F10HTR4 | |
| SCHEMBL6986867 | 0.89 | ROCK2 (0.41) | FAAHACHEROCK2F10HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |