Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5913864 | 0.87 | CA12 (0.51) | SMN1; SMN2KMT2AGAA | |
| SCHEMBL6987265 | 0.85 | KMT2A (0.57) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL18159264 | 0.80 | MTNR1A (0.50) | GAA | |
| SCHEMBL9689182 | 0.80 | CA12 (0.51) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1968355 | 0.78 | CA12 (0.66) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL4699337 | 0.74 | KMT2A (0.39) | SMN1; SMN2TDP1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4699335 | 0.74 | KMT2A (0.39) | SMN1; SMN2TDP1KMT2AMEN1L3MBTL1 | |
| SCHEMBL16416372 | 0.74 | CA12 (0.51) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21579855 | 0.74 | POLB (0.65) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL18159266 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2L3MBTL1GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558677-A1 | BIOLOGICALLY ACTIVE AMINES | Astra Pharmaceuticals Limited (GB) | 1993-09-08 | — | — | EP | disclosed |