Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028336 | 0.85 | KCNH2 (0.47) | MCHR1KCNH2 | |
| SCHEMBL6995893 | 0.84 | KCNH2 (0.40) | KCNH2MMP2HRH3 | |
| SCHEMBL6990334 | 0.82 | HRH2 (0.38) | KCNH2MMP2HRH3 | |
| SCHEMBL7034656 | 0.82 | MCHR1 (0.47) | MCHR1KCNH2MMP2ANPEP | |
| SCHEMBL6992363 | 0.80 | KCNH2 (0.40) | KCNH2MMP2HRH3 | |
| SCHEMBL7027091 | 0.80 | MCHR1 (0.49) | MCHR1KCNH2MAPTHRH3 | |
| SCHEMBL6994724 | 0.79 | HRH2 (0.42) | KCNH2HRH3 | |
| SCHEMBL6093884 | 0.79 | KCNH2 (0.49) | MCHR1KCNH2 | |
| SCHEMBL6093886 | 0.79 | KCNH2 (0.49) | MCHR1KCNH2 | |
| SCHEMBL6742864 | 0.77 | KCNH2 (0.44) | MCHR1KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301510-A1 | NEW BISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004446-A1 | NEW BISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2002-01-17 | — | — | WO | disclosed |