Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093886 | 0.94 | KCNH2 (0.49) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6093884 | 0.94 | KCNH2 (0.49) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2966825 | 0.90 | KCNH2 (0.59) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6742864 | 0.88 | KCNH2 (0.44) | KCNH2MCHR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6622817 | 0.87 | LMNA (0.44) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5965433 | 0.86 | KCNH2 (0.45) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5965590 | 0.86 | MCHR1 (0.46) | KCNH2MCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL7027091 | 0.86 | MCHR1 (0.49) | KCNH2MCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6738037 | 0.86 | CHRNA7 (0.47) | KCNH2MCHR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6987304 | 0.85 | MCHR1 (0.46) | KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | KCNH1, LBR, CACNA1E | KCNH2 7/4885MCHR1 1346/4885ALDH1A1 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.