Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 10/20 | 0.38 |
| ▸ | HRH1 | P35367 | 10/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995893 | 0.87 | KCNH2 (0.40) | KCNH2HRH2HRH1HRH3KDM1A | |
| SCHEMBL6994724 | 0.85 | HRH2 (0.42) | KCNH2HRH2HRH1HRH3KDM1A | |
| SCHEMBL6990334 | 0.85 | HRH2 (0.38) | KCNH2HRH2HRH1HRH3KDM1A | |
| SCHEMBL6989126 | 0.84 | KCNH2 (0.54) | KCNH2HRH2HRH1HRH3POLB | |
| SCHEMBL6987304 | 0.80 | MCHR1 (0.46) | KCNH2HRH3MMP2 | |
| SCHEMBL7030390 | 0.80 | KCNH2 (0.43) | KCNH2HRH2HRH1HRH3MMP2 | |
| SCHEMBL6989155 | 0.79 | HRH3 (0.48) | HRH2HRH1HRH3MEN1 | |
| SCHEMBL7089730 | 0.78 | KCNA5 (0.36) | KCNH2KDM1AMMP2MMP3MEN1 | |
| SCHEMBL6094368 | 0.77 | HRH3 (0.45) | KCNH2HRH2HRH1HRH3POLB | |
| SCHEMBL6094373 | 0.77 | HRH3 (0.45) | KCNH2HRH2HRH1HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301510-A1 | NEW BISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004446-A1 | NEW BISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2002-01-17 | — | — | WO | disclosed |