Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 4/20 | 0.45 |
| ▸ | HTR1B | P28222 | 4/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990553 | 0.99 | AVPR2 (0.47) | AVPR2AVPR1ACDK4CCND1ROCK2 | |
| SCHEMBL1495892 | 0.86 | AVPR2 (0.50) | AVPR2AVPR1ARAB9ASMN1; SMN2PDCD1 | |
| SCHEMBL7019597 | 0.84 | ROCK2 (0.46) | AVPR2AVPR1AROCK2DHODHRAB9A | |
| SCHEMBL7019311 | 0.84 | ROCK2 (0.46) | AVPR2AVPR1AROCK2RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6986424 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1ARAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6994121 | 0.82 | AVPR2 (0.46) | AVPR2AVPR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6993115 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1ARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6991735 | 0.81 | HTR1D (0.45) | CDK4CCND1ROCK2HTR1DHTR1B | |
| SCHEMBL1821311 | 0.80 | AVPR2 (0.56) | AVPR2AVPR1APDCD1CD274POLB | |
| SCHEMBL6987926 | 0.79 | AVPR2 (0.68) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |