Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495892 | 0.88 | AVPR2 (0.50) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6987369 | 0.81 | AVPR2 (0.47) | AVPR2AVPR1ASMN1; SMN2RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL6990553 | 0.81 | AVPR2 (0.47) | AVPR2AVPR1ASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL2704973 | 0.80 | AVPR2 (0.44) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6986559 | 0.79 | AVPR1A (0.62) | AVPR2AVPR1A | |
| SCHEMBL1821311 | 0.79 | AVPR2 (0.56) | AVPR2AVPR1AALDH1A1MAPTMAPK1 | |
| SCHEMBL2704977 | 0.79 | PDCD1 (0.46) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6993820 | 0.78 | AVPR1A (0.61) | AVPR2AVPR1A | |
| SCHEMBL7352575 | 0.78 | ALDH1A1 (0.56) | HPGDNPC1RAB9AL3MBTL1ALDH1A1 | |
| Conivaptan SCHEMBL4625101 | 0.78 | AVPR2 (0.75) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |