Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983685 | 0.86 | ACHE (0.47) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3843646 | 0.78 | NPSR1 (0.37) | NPSR1ELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL8152251 | 0.76 | TAAR1 (0.50) | ELANEMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2482136 | 0.74 | NPC1 (0.50) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7682170 | 0.74 | NPC1 (0.50) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30807386 | 0.74 | CYP3A4 (0.51) | ALDH1A1KDM4EHSD17B10CYP3A4TAAR1 | |
| SCHEMBL43253 | 0.74 | CYP3A4 (0.51) | ALDH1A1KDM4EHSD17B10CYP3A4TAAR1 | |
| SCHEMBL2481231 | 0.73 | NPC1 (0.48) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6987389 | 0.72 | ELANE (0.42) | ELANEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL25281976 | 0.71 | CYP3A4 (0.76) | HSD17B10CYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |